c-GAMMA: Comparative Genome Analysis of Molecular Markers
نویسندگان
چکیده
Discovery of molecular markers for efficient identification of living organisms remains a challenge of high interest. The diversity of species can now be observed in details with low cost genomic sequences produced by new generation of sequencers. A method, called c-GAMMA, is proposed. It formalizes the design of new markers for such data. It is based on a series of filters on forbidden pairs of words, followed by an optimization step on the discriminative power of candidate markers. First results are presented on a set of microbial genomes. The importance of further developments are stressed to face the huge amounts of data that will soon become available in all kingdoms of life.
منابع مشابه
Transferability of barley microsatellite markers for assessing genetic relationships of wheat wild relatives of Triticum and Aegilops genera
Comparative genomics has revealed a high degree of collinearity between related species, which allows transferability of interspecies and intergenus markers. The aim of this study was to examine the transferability of barley microsatellite markers among species of Triticum and Aegilops genus for determination of their genetic relationships. The experiments was carried out in faculty of agricu...
متن کاملDetermination of Genetic diversity of cultivated chickpea (Cicer arietinum L.) using Medicago truncatula EST-SSRs
Expressed sequence tags simple sequence repeats (EST-SSRs) are important sources for investigation of genetic diversity and molecular marker development. Similar to genomic SSRs, the EST-SSRs are useful markers for many applications in genetics and plant breeding such as genetic diversity analysis, molecular mapping and cross-transferability across related species and genera. In spite of low po...
متن کاملThe Impact of Different Genetic Architectures on Accuracy of Genomic Selection Using Three Bayesian Methods
Genome-wide evaluation uses the associations of a large number of single nucleotide polymorphism (SNP) markers across the whole genome and then combines the statistical methods with genomic data to predict the genetic values. Genomic predictions relieson linkage disequilibrium (LD) between genetic markers and quantitative trait loci (QTL) in a population. Methods that use all markers simultaneo...
متن کاملMolecular and morphological assessment of genetic variability induced by gamma radiation in canola
Mutation induction is considered as an effective way to enrich plant genetic variation, particularly for traits with a very low level of genetic variation. This research was conducted to assess genetic variation induced by gamma radiation in M2 and M3 mutant lines of canola (Brassica napus L.) by SSR and morphological characteristics and to identify useful mutants in terms of agronomic traits. ...
متن کاملAnalysis of genetic diversity, phylogenetic relationships and population structure of Arasbaran cornelian cherry (Cornus mas L.) genotypes using ISSR molecular markers
Cornelian cherry (Cornus mas L.), considered as the ancestor of cultivated trees in Arasbaran region, is a medicinally and economically plant species. However, little is known about genetic diversity, breeding programs, and population structure of this species in mentioned region. Keeping this in view, the main objectives of present study were to analysis the genetic diversity, phyloge...
متن کامل